10 Risk Factors For Leaky Gut Syndrome

Leaky gut syndrome is a condition that has become increasingly more common, yet it is not often discussed openly. If you are experiencing any of the symptoms associated with leaky gut, it is important to understand what could be causing it. In this blog post, we will discuss the potential causes of leaky gut syndrome and the steps you can take to address the problem.

Leaky gut syndrome is an increasingly common digestive disorder that has been linked to a range of physical and mental health issues. Don’t ignore the signs: learn about the possible causes of leaky gut and how to manage it.

Small intestinal bacterial overgrowth (SIBO)

Small intestinal bacterial overgrowth (SIBO) is a condition in which there is an excessive amount of bacteria in the small intestine. It is believed to be a major cause of leaky gut syndrome, and is often difficult to diagnose.

SIBO is typically caused by an imbalance of bacteria in the small intestine. This can be due to a weakened immune system or the use of antibiotics or steroids. It can also be caused by a decrease in digestive enzymes that help break down food, or an obstruction in the small intestine that prevents the normal passage of food.

Poor Diet

The foods we eat can have a significant impact on our gut health and the severity of leaky gut syndrome. Eating too many processed, refined and sugary foods can lead to inflammation in the gut. This inflammation increases the permeability of the intestinal walls, leading to leaky gut. Additionally, diets that are low in fiber can also contribute to poor gut health.

Eating a balanced diet with plenty of fiber and avoiding problem foods is a key part of managing leaky gut syndrome. Paying attention to what you eat and eliminating potentially inflammatory foods can help keep your gut healthy and reduce the symptoms of leaky gut syndrome.


Infections, both viral and bacterial, can also be a factor in developing leaky gut syndrome. Viruses, such as Epstein-Barr virus, cytomegalovirus, and herpes simplex virus, can cause inflammation in the gut lining and impair the tight junctions. Bacterial infections, such as those caused by Clostridia or Salmonella, can also damage the intestinal wall and disrupt the tight junctions. In addition, fungal infections such as Candida albicans can cause leaky gut syndrome by triggering an immune response and increasing intestinal permeability.

If you suspect that an infection is causing your leaky gut syndrome, it is important to consult your doctor for proper diagnosis and treatment. Ignoring an infection can lead to more serious health complications.

Food Sensitivities

Food sensitivities can be an underlying cause of leaky gut syndrome. They are caused by an immune system response to certain foods, which triggers the release of inflammatory chemicals that damage the gut lining. This damage can lead to increased intestinal permeability, allowing toxins and bacteria to pass through the intestinal wall.

By identifying and avoiding trigger foods, as well as taking supplements to support gut health, people with leaky gut syndrome can reduce their symptoms and improve their overall health.

Heavy Alcohol Consumption

Alcohol consumption can have a significant effect on the health of your gut and can ultimately lead to leaky gut syndrome. Excessive drinking can contribute to the weakening of the intestinal barrier, leading to increased intestinal permeability. Alcohol consumption has been shown to cause the death of some gut bacteria, which can disrupt the normal balance of beneficial bacteria in the gut.

Alcohol can also cause inflammation in the gut lining, further weakening the intestinal barrier. When the intestinal barrier is weakened and becomes more permeable, it allows toxins and microbes to pass through and enter the bloodstream, leading to leaky gut syndrome. Therefore, it is essential to practice moderation when consuming alcohol and limit excessive drinking.

Use of NSAIDs

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Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used for pain relief, but their use can also have negative effects on your health, including contributing to leaky gut syndrome. NSAIDs work by blocking the production of inflammatory chemicals, but they can also inhibit the natural healing process of your intestines. This can lead to increased intestinal permeability, which in turn can lead to leaky gut syndrome.

It is important to speak with your doctor before discontinuing the use of NSAIDs. But if you’ve been using them regularly and are suffering from symptoms of leaky gut syndrome, it may be worth exploring other options for pain relief that don’t involve the use of NSAIDs. Eating a balanced diet and getting regular exercise can also help reduce inflammation and improve digestion.


Chronic stress is an all-too-common problem in modern life, and it can have a negative effect on your gut health. Stress hormones, such as cortisol, can disrupt the balance of beneficial bacteria in the gut and weaken the protective barrier in the intestine, leading to increased permeability or “leaky gut.” When this happens, toxic substances and bacteria can pass through the intestinal wall, causing inflammation and a variety of symptoms.

Other Autoimmune Disorders

Suffering from autoimmune disorders like Hashimoto’s disease, lupus, multiple sclerosis, and rheumatoid arthritis can put you at risk of getting leaky gut syndrome since these compromise the gut lining and allow undigested food particles into the blood circulation.

You’ll never know where it will hit you…

Toxin Overload

Toxin overload can lead to increased intestinal permeability. Humans are exposed daily to up to 80,000 chemicals and other toxic substances found in things like personal care products, pesticides, and even contaminated tap water.

Some factors are invisible to the naked eye and much harder to deal with…


Prolonged exposure to stress and bouts of anxiety and depression can negatively impact the immune system and thin out the intestinal lining, resulting in chronic inflammation, potentially damaging the nervous system.

What you thought could bring relief can sometimes bring more problems…

Taking Antibiotics

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Antibiotics are necessary for eliminating infections, but taking them has some downsides too. Some antibiotics can change the gut microbiota, which can lead to bacteria overgrowth, possibly triggering dysbiosis.


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